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Bone Mineral Density (BMD) of 359 healthy Isfahani women
aged 23-60 years were compared with the Caucasians, Tehranis and some
Arab women. BMD was determined using dual energy X-ray absorptiometry
(DXA) at the lumbar spine and proximal femur. Age related changes in BMD
were similar to those described in Lebanese and Saudis for the femur,
Lebanese having the lowest femur BMD. However, the age related values
for the spine were similar for all populations, having the lowest BMD
values for the Isfahani women. The problem of using manufacture provided
reference data was investigated. In fact using the manufacture provided
reference data for the femoral neck diagnosed only 14.9% of the postmenopausal
women as normal due to improper use of T-score, while using the Isfahan
normative data 41.9% of the postmenopausal women were diagnosed as normal.
The normative peak BMD values acquired for Iranian women in Isfahan and
Tehran were different, in particular for the spine. The normative BMD
values in Isfahan were only acquired for the young women. Therefore, for
the management of patients, determining the secondary causes of osteoporosis
(Z-scores<-2) it is highly recommended to establish the normal range
for the entire age range of 20-80 years normal women and make further
investigations to find the reason(s) for the discrepancies in the normal
BMD ranges of women in Iran.