Search. Read. Cite.

Easy to search. Easy to read. Easy to cite with credible sources.

Short Communication
Identification of Free Fatty Acid Receptors GPR40/FFAR1 and GPR120/FFAR4 in a Domestic Cat

Makoto Habara, Makoto Tamanuki, Shingo Ishikawa, Hiroshi Takemitsu, Nobuko Mori, Yuki Okada, Nobuhiro Nakao, Koh Kawasumi, Katsumi Ishioka, Toshiro Arai and Ichiro Yamamoto

Asian Journal of Animal and Veterinary Advances, 2015, 10(4), 185-190.

Abstract

G-protein-coupled receptors (GPRs) 40 and 120 are members of the Free Fatty Acid (FFA) receptor group and are termed FFAR1 and FFAR4, respectively. The aim of this study was to clone cat GPR40 and GPR120 cDNAs in several tissues. There was high sequence homology to other mammalian GPR40 and GPR120, with encoding 320 and 361 amino acid residues, respectively. Cat GPR40 encoded extra 21 amino acid residues in the C-terminal cytoplasmic region. Quantitative RT-PCR revealed expression of GPR40 mRNA in the duodenum, liver and pancreas. The GPR120 mRNA was expressed in adipose tissues, cerebral cortex and colon. In conclusion, GPR40 and GPR120 were well conserved and were expressed in cat tissues with different distribution patterns.

ASCI-ID: 13-730

Cited References Fulltext

Related Articles

Treatment of Spinal Luxation in Cat

Asian Journal of Animal and Veterinary Advances, 2012, 7(1), 100-104.

Enrichment of Broiler Meat with n-3 Polyunsaturated Fatty Acids

Asian Journal of Animal and Veterinary Advances, 2008, 3(2), 70-77.

Effects of Dietary Canola Seed with Rosemary Supplementation on Growth Performance, Lipid Oxidation and Meat Fatty Acid Composition of Broilers

Asian Journal of Animal and Veterinary Advances, 2016, 11(12), 815-823.

Cited By

Molecular characterization of free fatty acid receptors FFAR2 and FFAR3 in the domestic cat

Veterinary Medicine and Science, 2020, (), . DOI: 10.1002/vms3.356