LATERAL ORGAN FUSION1 and LATERAL ORGAN FUSION2 function in lateral organ separation and axillary meristem formation in Arabidopsis
D. K Lee,
P. S. Springer
2009, 136(14), 2423-2432. DOI: 10.1242/dev.031971
Dong-Keun Lee, Matt Geisler, and Patricia S. Springer
Plant organs are generated from meristems throughout development.
Patterning and elaboration of organ primordia occur as a result of organized
cell division and expansion, processes that are likely to be controlled, in
part, by meristem-derived signals. Communication between the meristem and
lateral organs is crucial for meristem maintenance and organ patterning, and
organ boundaries are thought to be important for mediating this communication.
Arabidopsis thaliana LATERAL ORGAN FUSION1 (LOF1) encodes a
MYB-domain transcription factor that is expressed in organ boundaries.
lof1 mutants display defects in organ separation as a result of
abnormal cell division and expansion during early boundary formation.
lof1 mutants also fail to form accessory shoot meristems. Mutations
in the closely related LATERAL ORGAN FUSION2 (LOF2) gene
enhance the lof1 phenotype, such that lof1 lof2 double
mutants display additional fusion defects. Genetic interactions with the
CUP-SHAPED COTYLEDON genes CUC2 and CUC3 revealed a
role for LOF1 in both organ separation and axillary meristem
formation. Expression of the meristem determinant STM was reduced in