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Mohammad Sharifzadeh, Mahsa Raoufi, Amir Abbas Zahedinejad, Nourollah Aghaebrahimi, Kurdistan Sharifzadeh and Mohammad Abdollahi
International Journal of Pharmacology, 2005, 1(1), 74-78.
The effects of chronic lead acetate treatment on alterations of Auditory Brainstem Response (ABR) induced by gentamicin and amikacin were tested in guinea pigs. This study was designed to investigate the hypothesis that aminoglycoside antibiotics and lead via their effects on phosphoinositide pathway and calcium channels may influence ototoxicity mechanisms as tested on the auditory brainstem response. Intramuscular injection of different doses of gentamicin (5, 10 mg/kg/day) and amikacin (150, 300 mg/kg/day) for three weeks induced hearing loss. Administration of lead acetate (0.05%, 35 days) in drinking water changed ABR (absolute wave latency). The gentamicin-induced alteration of ABR were attenuated by chronic lead acetate pretreatment in guinea pig. Obtained data suggest the interactions between chronic lead acetate and aminoglycoside antibiotics in alterations of auditory functions which could be accounted for, at least partially, by perturbations of the phosphoinositide and calcium cascades within the inner ear.
ASCI-ID: 23-104
International Journal of Pharmacology, 2005, 1(1), 98-103.
Inhibitory Activities of New Series of 4, 5-diaryl Thiadiazoles Derivatives on Lipopolysaccharide-induced Cox-2 ExpressionInternational Journal of Pharmacology, 2005, 1(1), 79-84.
Modulation of MDR1 Gene Expression by a Chronic Treatment with Verapamil in Caco-2 CellsInternational Journal of Pharmacology, 2005, 1(1), 85-92.
Mucosal Protective Effects of Vitamin E on Aspirin-induced Gastric Lesions in RatsInternational Journal of Pharmacology, 2005, 1(1), 93-97.
Effects of NADH Supplementation on Hematological and Blood Biochemical Parameters and Tissue Oxidant/Antioxidant Status in RatsInternational Journal of Pharmacology, 2005, 1(1), 71-73.
Differential Regulation of Gap Junction Proteins Connexin 40 and Connexin 43 in CardiomyocytesInternational Journal of Pharmacology, 2005, 1(1), 44-54.
Dietary Flavonoid Phloretin Modulates Ca2+-activated K+ Channels Resulting in an Increase of Endothelial Nitric Oxide ProductionInternational Journal of Pharmacology, 2005, 1(1), 38-43.
PDGF-BB Induced Modulation of Ca2+-Activated K+ Channels Involves a G-Protein Dependent Mechanism in Cultured Human Endothelial CellsInternational Journal of Pharmacology, 2005, 1(1), 33-37.
Pharmacokinetics and Tolerance of Thiamphenicol in Camels and SheepInternational Journal of Pharmacology, 2005, 1(1), 25-28.
Coumarin Derivatives and Oxidative StressInternational Journal of Pharmacology, 2005, 1(1), 29-32.
Biologic Management of Fistulizing Crohn’s DiseaseInternational Journal of Pharmacology, 2005, 1(1), 17-24.
The Adverse Drug Reaction in the Gastrointestinal Tract: An OverviewInternational Journal of Pharmacology, 2005, 1(1), 1-8.
Future Drugs for Treatment of Acute Respiratory Distress SyndromeInternational Journal of Pharmacology, 2005, 1(1), 9-16.
Gabapentin Increases Analgesic Effect of Chronic Use of Morphine while Decreases Withdrawal SignsInternational Journal of Pharmacology, 2005, 1(2), 161-166.
Effect of Pilocarpine and Angiotensin II on Salivary Flow, Total Protein and Electrolyte Concentrations of SalivaInternational Journal of Pharmacology, 2005, 1(2), 190-194.
Gender Related Differences in Antinociceptive Properties of Morphine after Gonadectomy in Male and Female RatsInternational Journal of Pharmacology, 2005, 1(2), 167-171.
Testing the Awareness of Hazardous Nature of Printmaking Materials among Printmaking Instructors in Traditional and Non-toxic Printmaking ProgramsInternational Journal of Pharmacology, 2005, 1(2), 152-156.
Protective Effects of Sildenafil and Dipyridamol from Lead-induced Lipid Peroxidation in Perfused Rat LiverInternational Journal of Pharmacology, 2005, 1(2), 157-160.
Therapeutic Implications of Blockers of Advanced Glycation End Products (AGEs)-their Receptor (RAGE) SystemInternational Journal of Pharmacology, 2005, 1(2), 203-209.
Lornoxicam Inhibits Human Polymorphonuclear Cell Migration Induced by fMLP, Interleukin-8 and Substance PInternational Journal of Pharmacology, 2005, 1(2), 180-184.
What is the Opposite of a Receptor Reserve?International Journal of Pharmacology, 2005, 1(2), 195-202.
Alterations in Hepatic Cholesterol Levels in Response to Drugs That Induce Cytochrome P450 3A23International Journal of Pharmacology, 2005, 1(2), 172-179.
Novel Topoisomerase I and II Inhibitors, Parameritannins A-2 and A-3, are Selective Human Cancer CytotoxinsInternational Journal of Pharmacology, 2005, 1(2), 138-151.
Effects of Indigenous Medicinal Plants (Neem and Pineapple) Against Gastro-intestinal Nematodiasis in SheepInternational Journal of Pharmacology, 2005, 1(2), 185-189.
Anti-inflammatory Activities of Methanolic Extracts of Stachys persica and Stachys setifera on Rats and MiceInternational Journal of Pharmacology, 2005, 1(2), 132-137.
Optimal Agonist/Antagonist Combinations Maintain Receptor Response by Preventing Rapid β1-adrenergic Receptor DesensitizationInternational Journal of Pharmacology, 2005, 1(2), 122-131.
Psorospermum Febrifugum Spach (Hypericaceae) Decoction Antagonized Chemically-induced Convulsions in MiceInternational Journal of Pharmacology, 2005, 1(2), 118-121.
Studying the Role of P-glycoprotein in Resistance to Tamoxifen in Humen Breast Cancer T47D Cells by ImmunocytochemistryInternational Journal of Pharmacology, 2005, 1(2), 112-117. DOI:
Expression of Thymidylate Synthase and Thymidine Phosphorylase as Prognostic Markers in Advanced Esophageal Squamous Cell CarcinomaInternational Journal of Pharmacology, 2005, 1(2), 104-111.
Adverse Effects of StatinsInternational Journal of Pharmacology, 2005, 1(3), 210-225.
Development of Chymase Inhibitor as a Potent Agent for Preventing Vascular DiseasesInternational Journal of Pharmacology, 2005, 1(3), 281-286.
Demystifying Phytochemicals: An InsightInternational Journal of Pharmacology, 2005, 1(3), 234-238.
Investigation of Comparative Hypoglycemic Effect of Neem (Azadirachta indica), Karala (Momordica charantea) and Nayantara (Cathranthus roseus) with Glibenclamide on RatInternational Journal of Pharmacology, 2005, 1(3), 257-260.
Protective Activity of Turmeric (Curcuma longa) in Paracetamol-induced Hepatotoxicity in RatsInternational Journal of Pharmacology, 2005, 1(3), 252-256.
Anti-pyretic and Analgesic Activity of Zingiber zerumbetInternational Journal of Pharmacology, 2005, 1(3), 277-280.
Synthesis and Anti-inflammatory Evaluation of Some New Quinazoline DerivativesInternational Journal of Pharmacology, 2005, 1(3), 261-266.
Comparative Evaluation of Hypoglycaemic Activity of Two Medicinal Plants in Alloxan Diabetic RatsInternational Journal of Pharmacology, 2005, 1(3), 267-276.
Abuse of Dextromethorphan: Review and A Case ReportInternational Journal of Pharmacology, 2005, 1(3), 293-295.
Antioxidants: Their Role in Health and DiseaseInternational Journal of Pharmacology, 2005, 1(3), 226-233.
Gonadal Responses to Antipsychotic Drugs: Chlorpromazine and Thioridazine Reversibly Suppress Testicular Functions in Albino RatsInternational Journal of Pharmacology, 2005, 1(3), 287-292.
16 α Hydroxy-(-)-kauran-19-oic Acid: An Antibacterial Diterpene from Sweet Apple (Annona squamosa L., Annonaceae)International Journal of Pharmacology, 2005, 1(3), 296-298.
Residues of Sulphadimidine and its Metabolite N4-acetyl in Camel MilkInternational Journal of Pharmacology, 2005, 1(3), 249-251.
Pharmacokinetics of Chloramphenicol Following Intravenous and Intramuscular Administration of the Drug to Healthy Sokoto Red GoatsInternational Journal of Pharmacology, 2005, 1(3), 239-243.
Pharmacokinetics of Chloramphenicol in Healthy and Water-deprived GoatsInternational Journal of Pharmacology, 2005, 1(3), 244-248.
The Anti-inflammatory Activity of the Foeniculum vulgare L. Essential Oil and Investigation of its Median Lethal Dose in Rats and MiceInternational Journal of Pharmacology, 2005, 1(4), 329-331.
Functional Characterization of a K140N Human Glucocorticoid Receptor VariantInternational Journal of Pharmacology, 2005, 1(4), 316-323.
Determination of Rofecoxib in Serum with Pre-column Derivatization and Fluorescence DetectionInternational Journal of Pharmacology, 2005, 1(4), 332-335.
Protective Effects of Polygonum viviparum L. Root and its Extracts Against Lipid-peroxidation Induced by Indomethacin in RatsInternational Journal of Pharmacology, 2005, 1(4), 324-328.
Different Profile of Propranolol and Amitriptyline Effects on Migraine ProphylaxisInternational Journal of Pharmacology, 2005, 1(4), 366-368.
Does the Binding Duration of a Partial α2-adrenoceptor Agonist Exceed its Activation Interval at the Autoreceptor?International Journal of Pharmacology, 2005, 1(4), 299-310.
Neuroprotection in Acute Ischemia and Ischemia/Reperfusion in Rat RetinaInternational Journal of Pharmacology, 2005, 1(4), 369-375.
A Possible Modulatory Role of Nitric Oxide in Paraquat-induced Lung Injury in MiceInternational Journal of Pharmacology, 2005, 1(4), 360-365.
Is Dexamethasone a Suitable Alternative for Dihydroergotamine on Migraine Attacks?International Journal of Pharmacology, 2005, 1(4), 357-359.
The Protective Effects of Antioxidants and Propranolol on Hepatotoxicity of TCDD During Isolated Rat Liver PerfusionInternational Journal of Pharmacology, 2005, 1(4), 336-341.
The Effect of Sandostatin LAR in the Treatment of AcromegalyInternational Journal of Pharmacology, 2005, 1(4), 342-345.
A Comparison of the Sensory and Motor Blockade Duration of Intrathecal Lidocaine 5%, Lidocaine 5% Plus Epinephrine and Lidocaine 5% Plus Dexamthasone: A Double Blind Randomized Clinical Trials StudyInternational Journal of Pharmacology, 2005, 1(4), 346-349.
Tracheal Responsiveness to Histamine and Histamine (H1) Receptor Blockade by Chlorpheniramine in an Animal Model of COPDInternational Journal of Pharmacology, 2005, 1(4), 350-356.
Toxic Reactions to Chronic Use of Benzodiazepines: An OverviewInternational Journal of Pharmacology, 2005, 1(4), 376-382.
The Antiplaque Effects of Salvadora persica and Padina Essential Oil Solution in Comparison to Chlorhexidine in Human Gingival Disease; a Randomized Placebo-controlled Clinical TrialInternational Journal of Pharmacology, 2005, 1(4), 311-315.
A Review on Native Medicinal Plants in Khuzestan, Iran with Antibacterial PropertiesInternational Journal of Pharmacology, 2010, 6(5), 551-560.
How Some Melanoma Tumors Evade Drug Treatment: Critical Gene Involved in Melanoma GrowthInternational Journal of Pharmacology, 2011, 7(2), 291-292.
Coffee and a Sweet Treat to Think Better? Caffeine and Glucose Combined Improves the Efficiency of Brain ActivitydInternational Journal of Pharmacology, 2011, 7(2), 293-293.
Will Herbal Ingredients Work for Drug-induced Hyperprolactinemia?International Journal of Pharmacology, 2011, 7(4), 544-545.
Does it Make a Difference Which Interferon-β to use for Relapse and Remitting Multiple Sclerosis (RRMS)?International Journal of Pharmacology, 2011, 7(4), 542-543.
Pouchitis: An Empirically Treated Disease in the Era of Evidence-based MedicineInternational Journal of Pharmacology, 2011, 7(5), 550-551.
Advances on the Pharmacological use of Teucrium spp. (Germanders)International Journal of Pharmacology, 2011, 7(5), 548-549.
Are Iron Chelators Safe to Be Used in Hyperoxia-induced Lung Injury?International Journal of Pharmacology, 2011, 7(5), 546-547.
Cassia nigricans have Potential against Pathogenic MicroorganismsInternational Journal of Pharmacology, 2011, 7(6), 672-672.
In vitro Antioxidant Activity of Itrifal Kishneezi: A Unani FormulationInternational Journal of Pharmacology, 2011, 7(6), 673-673.
Successes in Understanding Pathophysiology of OsteoporosisInternational Journal of Pharmacology, 2011, 7(6), 677-678.
New Horizons in Management of Inflammatory Bowel DiseaseInternational Journal of Pharmacology, 2011, 7(6), 679-681.
Methanolic Extract of Croton Penduliflorus Affects Intestinal Enzyme Activity and Protein Content in the Late Phase of PregnancyInternational Journal of Pharmacology, 2011, 7(6), 670-670.
Gynandropsis pentaphylla DC Extracts on the Production of Microbial ProteinsInternational Journal of Pharmacology, 2011, 7(6), 674-674.
How Much Chronic Exposure to Aluminum and its Toxicity Should be Concerned in Current Human Life?International Journal of Pharmacology, 2011, 7(6), 675-676.
Ampucare Performed Good Antimicrobial Activity under All Storage ConditionsInternational Journal of Pharmacology, 2011, 7(6), 671-671.
Silybum marianum L. Despite of its Weedy Nature is an Important Medicinal Plant of NWFP, PakistanInternational Journal of Pharmacology, 2011, 7(7), 747-748.
Hypoglycemic Property of Satureja khuzestanica in Human Still in DoubtInternational Journal of Pharmacology, 2011, 7(7), 745-746.
Parquetina nigrescens Checks the Ulceration and OxidationInternational Journal of Pharmacology, 2011, 7(7), 797-798.
A Comparison between the use and Availability of Antidotes in Iran and United States of AmericaInternational Journal of Pharmacology, 2011, 7(8), 799-800.
Self-medication: Risks and BenefitsInternational Journal of Pharmacology, 2012, 8(1), 58-59.
Agonist Concentration-response Models in Mouse and Rabbit Neocortex: Re-evaluation of Classical Models in Comparison with a Recently Developed General Response FunctionInternational Journal of Pharmacology, 2005, 1(1), 55-70.
The Role of Environmental Pollution of Pesticides in Human DiabetesInternational Journal of Pharmacology, 2012, 8(2), 139-140.
Current Concerns on the Validity of in vitro Models that use Transformed Neoplastic Cells in Pharmacology and ToxicologyInternational Journal of Pharmacology, 2012, 8(6), 594-595.
Current Concerns on Genotoxicity of PesticidesInternational Journal of Pharmacology, 2012, 8(6), 473-474.
Concerns on the Use of Chromium in Type 2 Diabetes Mellitus; Needs to Conduct Major Meta-analysisInternational Journal of Pharmacology, 2012, 8(6), 470-472.
Does Mambalgins Obtained from Black Mamba Venom have Solution for Morphine Related Side-Effects?International Journal of Pharmacology, 2012, 8(7), 657-658.
Who Plays Dual Role in Cancerous and Normal Cells? Natural Antioxidants or Free Radicals or the Cell EnvironmentInternational Journal of Pharmacology, 2012, 8(8), 711-712.
Is There a Link Between Human Infertilities and Exposure to Pesticides?International Journal of Pharmacology, 2012, 8(8), 708-710.
The Pros and Cons of the In-silico Pharmaco-toxicology in Drug Discovery and DevelopmentInternational Journal of Pharmacology, 2013, 9(3), 176-181.
Research HighlightsInternational Journal of Pharmacology, 2013, 9(7), 454-461.
Saudi Journal of Biological Sciences, 2012, 19(1), 103. DOI: 10.1016/j.sjbs.2011.11.002