Search. Read. Cite.

Easy to search. Easy to read. Easy to cite with credible sources.

Research Article
Testicular Histopathological Alterations in Rats Treated with Sumithion® NP 25/2.5 EC, Insecticide

Mohammed O. Al-Jahdali and Ameen S. Bin Bisher

Journal of Biological Sciences, 2007, 7(3), 520-525.

Abstract

The histopathological changes induced by Sumithion® NP 25/2.5 EC, a newly formulated organophosphorous insecticide used in dengue fever vector control in Jeddah, Saudi Arabia, on rats testis were investigated. In addition to the control group, four experimental groups of male Wistar rats were daily injected intraperitoneally with two doses of Sumithion® NP 25/2.5 EC (1/10 and 1/4 the LD50; 80 and 200 mg kg-1 of body weight, respectively) for two and four weeks. Histological examination revealed significant alterations in the testis of all treated groups including: Focal mild testicular damages, blood hemorrhage and vascular congestion, hypospermatogenesis, dilatation and tubular deformity, cellular vacuolated degeneration (necrosis), aspermatogenesis and tubular destruction and atrophy. The observed pathological changes were dose and time dependent. The testicular toxicity of Sumithion® NP 25/2.5 EC was proven and alternative harmless control strategies should be applied.

ASCI-ID: 38-1397

Cited References Fulltext

Related Articles


Renal Lesions Induced by Pyrethroid Inhalation in Albino Rats

Journal of Biological Sciences, 2001, 1(11), 1066-1068.

Pathological Changes of Lung Tissues of Pigeons (Columba livia domestica) Infected with Haemoproteus columbae (Haemosporina: Haemoproteidae)

Journal of Biological Sciences, 2005, 5(5), 536-541.

Comparison of Different Laboratory Methods for Diagnosis of Helicobacter pylori

Journal of Biological Sciences, 2006, 6(6), 1146-1149.

The First Report of Intracranial Meningioma in a Donkey

Journal of Biological Sciences, 2007, 7(2), 462-463.

Hydroalcoholic Extract of Terminalia arjuna:A Potential Hepatoprotective Herb

Journal of Biological Sciences, 2007, 7(2), 255-262.

Inhibitory Effect of Melatonin on Histological Changes Induced in Rat Liver by Thioacetamide Intoxication

Journal of Biological Sciences, 2007, 7(1), 10-18.

Toxicity Studies on the Methanolic Extract of Portulaca oleracea L. (Fam. Portulacaceae)

Journal of Biological Sciences, 2007, 7(7), 1293-1295.

Antitumor Efficacy of Salenostemma Argel and/or γ-Irradiation Against Ehrlich Carcinoma

Journal of Biological Sciences, 2010, 10(6), 468-479.

Shell Diseases of Brachyuran Crabs

Journal of Biological Sciences, 2012, 12(3), 117-127.

Toxicological Effect of Single Treatment of Permethrin Injected into the Eggs on ‘0’ Day of Incubation on the Liver of Newly Hatched Chick

Journal of Biological Sciences, 2003, 3(7), 660-673.

Health Condition of a Farmed Tilapia (Oreochromis niloticus) in Earthen Ponds, Northern Bangladesh

Journal of Biological Sciences, 2012, 12(5), 287-293.

Gene Expression and Activities of Antioxidant Enzymes in Kidneys of Rats Intoxicated with Aflatoxin B1

Journal of Biological Sciences, 2016, 16(3), 65-71.

Serum Biochemical and Histopathological Changes Associated with Aeromonas hydrophila Isolated from Oreochromis niloticus and Sparus aurata with Multiple Antibiotic Resistance Index

Journal of Biological Sciences, 2017, 17(5), 222-234.

Rapid Detection and Control of Gram-negative Bacterial Pathogens Isolated from Summer Mortality Outbreak Affecting Tilapia Farms

Journal of Biological Sciences, 2019, 19(1), 24-33.

Hepatoprotective and Antioxidant Effect of Andrographis echioides N. against Acetaminophen Induced Hepatotoxicity in Rats

Journal of Biological Sciences, 2009, 9(4), 351-356.

Role of Garlic Extract in Alleviating Toxic Effects of Copper Sulfate in Claria gariepinus

Journal of Biological Sciences, 2020, 20(3), 123-133.

Unifocal Brown Tumor of Tibia: An Unusual Presentation

Journal of Biological Sciences, 2020, 20(3), 134-137.

Cajanus cajan (L) Mill Sp. Leaf Extract Exacerbates Acute Renal Injury Induced by Acetaminophen in Albino Rats

Journal of Biological Sciences, 2022, 22(1), 34-41.

Cited By


Response of blastocyst–endometrium interactions in albino rats to sublethal doses of biological and synthetic insecticides

Food and Chemical Toxicology, 2011, (), . DOI: 10.1016/j.fct.2011.06.063

How to Cope with Dengue in Developing Countries Like Pakistan?

Asian Journal of Animal and Veterinary Advances, 2011, 6(12), 1094. DOI: 10.3923/ajava.2011.1094.1124

Histomorphometric study of testis in deltamethrin treated albino rats

Toxicology Reports, 2014, 1(), 401. DOI: 10.1016/j.toxrep.2014.07.005

Toxicity assessment of Erythrophleum ivorense and Parquetina nigrescens

Toxicology Reports, 2014, 1(), 411. DOI: 10.1016/j.toxrep.2014.06.009

The effectiveness of supplemental administration of progesterone with GnRH, hCG and PGF2α on the fertility of Tuj sheep during the non-breeding season

Small Ruminant Research, 2013, 113(2-3), 365. DOI: 10.1016/j.smallrumres.2013.03.018

Intra-specific genetic diversity, phytochemical analysis and antioxidant activities of a potential Himalayan Swertia (Swertia bimaculata Hook. F. & Thomas.)

Industrial Crops and Products, 2013, 49(), 341. DOI: 10.1016/j.indcrop.2013.05.017

Pilot plant clarification of sweet sorghum juice and evaporation of raw and clarified juices

Industrial Crops and Products, 2013, 49(), 648. DOI: 10.1016/j.indcrop.2013.06.027

Morphological characterization, biomass and pharmaceutical compounds in Italian globe artichoke genotypes

Industrial Crops and Products, 2013, 49(), 326. DOI: 10.1016/j.indcrop.2013.05.015

Phytochemistry, antioxidant and antimicrobial activities of the essential oils of Mentha rotundifolia L. in Tunisia

Industrial Crops and Products, 2013, 49(), 883. DOI: 10.1016/j.indcrop.2013.06.032

Boundary identification in EBSD data with a generalization of fast multiscale clustering

Ultramicroscopy, 2013, 133(), 16. DOI: 10.1016/j.ultramic.2013.04.009

Ethanolic extract of Otostegia persica ameliorates bone loss in diabetic rats irrespective to its glucose lowering effect

Comparative Clinical Pathology, 2014, 23(5), 1147. DOI: 10.1007/s00580-013-1754-0

Serum biochemical and hematological reference values for lactating buffaloes

Comparative Clinical Pathology, 2014, 23(5), 1179. DOI: 10.1007/s00580-013-1760-2

Selected biochemical parameters in plasma of blood and semen of Persian sturgeon, Acipenser persicus

Comparative Clinical Pathology, 2014, 23(5), 1241. DOI: 10.1007/s00580-013-1769-6

Rhodanese distribution in different tissues of rabbits

Comparative Clinical Pathology, 2014, 23(5), 1259. DOI: 10.1007/s00580-013-1772-y

Phenological and physiological responses to drought stress and subsequent rehydration cycles in two raspberry cultivars

Scientia Horticulturae, 2013, 162(), 234. DOI: 10.1016/j.scienta.2013.07.025

Neural tube alteration in fetuses of diabetic rats

Comparative Clinical Pathology, 2014, 23(5), 1277. DOI: 10.1007/s00580-013-1775-8

Common bean (Phaseolus vulgaris L.) seedlings overcome NaCl stress as a result of presoaking in Moringa oleifera leaf extract

Scientia Horticulturae, 2013, 162(), 63. DOI: 10.1016/j.scienta.2013.07.046

Ultrastructural study on the photoreceptor layer in streptozotocin-induced diabetic rats

Comparative Clinical Pathology, 2014, 23(5), 1293. DOI: 10.1007/s00580-013-1777-6

Evaluation of genetic diversity in cucumber (Cucumis sativus L.) germplasm using agro-economic traits and microsatellite markers

Scientia Horticulturae, 2013, 162(), 278. DOI: 10.1016/j.scienta.2013.08.029

Effects of indole-3-acetic acid and auxin transport inhibitor on auxin distribution and development of peanut at pegging stage

Scientia Horticulturae, 2013, 162(), 76. DOI: 10.1016/j.scienta.2013.07.027

Antihyperlipidemic effects of mature coconut water and its role in regulating lipid metabolism in alloxan-induced experimental diabetes

Comparative Clinical Pathology, 2014, 23(5), 1331. DOI: 10.1007/s00580-013-1784-7

Impact of addition of biochar along with Bacillus sp. on growth and yield of French beans

Scientia Horticulturae, 2013, 162(), 351. DOI: 10.1016/j.scienta.2013.08.002

Evaluation of varying levels of acid-binding capacity of diets formulated with various acidifiers on physical and histological characteristics of leg bones in broiler chickens

Comparative Clinical Pathology, 2014, 23(5), 1409. DOI: 10.1007/s00580-013-1798-1

Effects of supplemental thyme extract (Thymus vulgaris L.) on growth performance, intestinal microbial populations, and meat quality in Japanese quails

Comparative Clinical Pathology, 2014, 23(5), 1503. DOI: 10.1007/s00580-013-1813-6

Bisphenol A and human health: A review of the literature

Reproductive Toxicology, 2013, 42(), 132. DOI: 10.1016/j.reprotox.2013.08.008

Influence of zinc supplementation on histopathological changes in the stomach, liver, kidney, brain, pancreas and spleen during subchronic exposure of Wistar rats to glyphosate

Comparative Clinical Pathology, 2014, 23(5), 1535. DOI: 10.1007/s00580-013-1818-1

An overview of freshwater snails in Asia with main focus on Vietnam

Acta Tropica, 2014, 140(), 105. DOI: 10.1016/j.actatropica.2014.08.005

Preferential feeding success of laboratory reared Anopheles stephensi mosquitoes according to ABO blood group status

Acta Tropica, 2014, 140(), 118. DOI: 10.1016/j.actatropica.2014.08.012

Heat transfer and flow characteristics of spiral fin-and-tube heat exchangers: A review

International Journal of Heat and Mass Transfer, 2014, 79(), 417. DOI: 10.1016/j.ijheatmasstransfer.2014.07.072

Transport via xylem and accumulation of aflatoxin in seeds of groundnut plant

Chemosphere, 2015, 119(), 524. DOI: 10.1016/j.chemosphere.2014.07.033

Avian feathers as a non-destructive bio-monitoring tool of trace metals signatures: A case study from severely contaminated areas

Chemosphere, 2015, 119(), 553. DOI: 10.1016/j.chemosphere.2014.06.068

Unpacking Postharvest Losses in Sub-Saharan Africa: A Meta-Analysis

World Development, 2015, 66(), 49. DOI: 10.1016/j.worlddev.2014.08.002

Protective effect of aged garlic extract against the oxidative stress induced by cisplatin on blood cells parameters and hepatic antioxidant enzymes in rats

Toxicology Reports, 2014, 1(), 682. DOI: 10.1016/j.toxrep.2014.09.003

The effects of garlic-supplemented diets on antibacterial activities against Photobacterium damselae subsp. piscicida and Streptococcus iniae and on growth in Cobia, Rachycentron canadum

Aquaculture, 2015, 435(), 111. DOI: 10.1016/j.aquaculture.2014.09.029

Trans- and cis-urocanic acid, biogenic amine and amino acid contents in ikan pekasam (fermented fish) produced from Javanese carp (Puntius gonionotus) and black tilapia (Oreochromis mossambicus)

Food Chemistry, 2014, (), . DOI: 10.1016/j.foodchem.2014.09.158

Understanding nitrile-degrading enzymes: classification, biocatalytic nature and current applications

Revista Latinoamericana de Biotecnología Ambiental y Algal, 2014, 5(1), . DOI: 10.7603/s40682-014-0002-x

Biodegradation of Methyl Orange by alginate-immobilized Aeromonas sp. in a packed bed reactor: external mass transfer modeling

Bioprocess and Biosystems Engineering, 2014, 37(11), 2149. DOI: 10.1007/s00449-014-1192-7

Enhancement of tannase production by Lactobacillus plantarum CIR1: validation in gas-lift bioreactor

Bioprocess and Biosystems Engineering, 2014, 37(11), 2305. DOI: 10.1007/s00449-014-1208-3

Agrobacterium tumefaciens-mediated genetic transformation of haptophytes (Isochrysis species)

Applied Microbiology and Biotechnology, 2014, 98(20), 8629. DOI: 10.1007/s00253-014-5900-7

Multiplex PCR in Species Authentication: Probability and Prospects—A Review

Food Analytical Methods, 2014, 7(10), 1933. DOI: 10.1007/s12161-014-9844-4

Determination of Phenolic Compounds in Artichoke, Garlic and Spinach by Ultra-High-Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry

Food Analytical Methods, 2014, 7(10), 2095. DOI: 10.1007/s12161-014-9852-4

Gentamicin release from biodegradable poly-l-lactide based composites for novel intramedullary nails

Materials Science and Engineering: C, 2014, 45(), 15. DOI: 10.1016/j.msec.2014.08.059

Multi-objective optimization of activated tungsten inert gas welding of duplex stainless steel using response surface methodology

The International Journal of Advanced Manufacturing Technology, 2014, (), . DOI: 10.1007/s00170-014-6426-y

C10H18N2Na2O10 inhibition and adsorption mechanism on concrete steel-reinforcement corrosion in corrosive environments

Journal of the Association of Arab Universities for Basic and Applied Sciences, 2014, (), . DOI: 10.1016/j.jaubas.2014.08.004

Effects of partially replacing dietary soybean meal or cottonseed meal with completely hydrolyzed feather meal (defatted rice bran as the carrier) on production, cytokines, adhesive gut bacteria, and disease resistance in hybrid tilapia (Oreochromis niloticus ♀ × O. aureus ♂)

Fish & Shellfish Immunology, 2014, (), . DOI: 10.1016/j.fsi.2014.09.039

Palm oil tocotrienol-rich fraction attenuates testicular toxicity induced by fenitrothion via an oxidative stress mechanism

Toxicol. Res., 2015, 4(1), 132. DOI: 10.1039/C4TX00090K

Chemical conversion pathways for carbohydrates

Green Chem., 2015, 17(1), 40. DOI: 10.1039/C4GC01062K

Characterisation of Toll-like receptors 4, 5 and 7 and their genetic variation in the grey partridge

Genetica, 2015, (), . DOI: 10.1007/s10709-015-9819-4

Alterations in gut microflora populations and brush border functionality following intra-amniotic daidzein administration

RSC Adv., 2015, 5(9), 6407. DOI: 10.1039/C4RA10962G

The molecular basis of -lactamase production in Gram-negative bacteria from Saudi Arabia

Journal of Medical Microbiology, 2015, 64(Pt_2), 127. DOI: 10.1099/jmm.0.077834-0

Fabrication of salt–hydrogel marbles and hollow-shell microcapsules by an aerosol gelation technique

J. Mater. Chem. B, 2015, 3(1), 82. DOI: 10.1039/C4TB01443J

Quantum Dynamics of Carbon Dioxide Encapsulated in the Cages of the sI Clathrate Hydrate: Structural Guest Distributions and Cage Occupation

The Journal of Physical Chemistry C, 2015, (), 150127124917004. DOI: 10.1021/jp5123745

Bioaccumulation of metals and metalloids in medicinal plant Ipomoea pes-caprae from areas impacted by tsunami

Environmental Toxicology and Chemistry, 2015, 34(2), 252. DOI: 10.1002/etc.2794

Null Steering of Adaptive Beamforming Using Linear Constraint Minimum Variance Assisted by Particle Swarm Optimization, Dynamic Mutated Artificial Immune System, and Gravitational Search Algorithm

The Scientific World Journal, 2014, 2014(), 1. DOI: 10.1155/2014/724639

Effectiveness of Hydrothermal-Calcium Chloride Treatment and Chitosan on Quality Retention and Microbial Growth during Storage of Fresh-Cut Papaya

Journal of Food Science, 2015, (), n/a. DOI: 10.1111/1750-3841.12783