Search. Read. Cite.

Easy to search. Easy to read. Easy to cite with credible sources.

Research Article
Prevalence and Antibiotic Susceptibility Patterns of Bloodstream Salmonella Infections in a Tertiary Care Hospital, Dhaka

Hafsa Afroz, Md. Manjur Hossain, Md. Fakruddin, Md. Afzal Hossain, Zahed Uddin Mahmood Khan and Suvamoy Datta

Journal of Medical Sciences, 2013, 13(5), 360-366.


Blood stream Salmonella infections range from self-limiting infections to life-threatening sepsis causing significant mortality and morbidity worldwide and require rapid and aggressive anti-microbial treatment. The antibiotic resistance pattern of Salmonella is ever changing over time. Rational and correct use of antibiotics requires understanding of the pathogen and drug resistance patterns in a community. This study was conducted to determine the status of bloodstream Salmonella infection and their antibiotic susceptibility patterns in a tertiary care hospital at Dhaka, Bangladesh. Six hundred and fifty six blood samples collected from clinically diagnosed enteric fever patients from Dhaka Medical college Hospital, Dhaka during January 2012 to December 2012 were processed. Salmonella enterica serovar typhi and paratyphi isolates were identified by standard microbiological and biochemical procedures. Ninty four isolates of Salmonella typhi and 59 isolates of S. paratyphi were isolated. Average prevalence rate of Salmonella in blood was 24.8%. Young, neonates and elderly persons are more prone to Salmonella infection and males are more susceptible to Salmonella septicemia than females. Most of the isolates Salmonella spp. were Multi-drug Resistance (MDR) and showed high resistance against cefixime, ceftriaxone, cefipime, ciprofloxacin, chloramphenicol and meropenem. Nalidixic acid was found to be effective against them. Specific antibiotic utilization strategies like antibiotic restriction, combination therapy and usage according to the standard antimicrobial susceptibility testing may help to decrease or prevent the emergence of resistance and incidence of blood stream infections.

ASCI-ID: 41-1187

Cited References Fulltext

Similar Articles

Prescribing Antibiotics by General and Specialist Physicians:A Pharmacist Administrated Survey

Journal of Medical Sciences, 2007, 7(3), 427-431.

Post Irradiation Effect on Adherent Growth,Slime Formation and Antibiotic Resistance of Pseudomonas aeruginosa Causing Human Infection

Journal of Medical Sciences, 2001, 1(4), 244-250.

Identification, Characterization and Antibiotic Susceptibility of Salmonella and Shigella species Isolated from Blood and Stool Samples of Patients Visiting N. I. H, Islamabad

Journal of Medical Sciences, 2002, 2(2), 85-88.

Evaluation of Home Slaughtered Meat Quality used for Human Consumption at Household and Food Seller House in Jimma

Journal of Medical Sciences, 2013, 13(8), 779-784.

A Brief Account of the Rules Applied to the Naming and Epidemiologically Grouping Salmonella Strains when Isolated from Animals

Journal of Medical Sciences, 2014, 14(3), 101-107.

Health Beliefs of Nurses about Breast Self Examination

Journal of Medical Sciences, 2006, 6(5), 743-750.

Susceptibility Testing of Clinical Mould Isolates in Malaysia with the E-test and M38-A Methods

Journal of Medical Sciences, 2008, 8(1), 94-97.

Susceptibility to Over Production of Cytokines in Acute Rheumatic Carditis and Their Role in the Pathogenesis

Journal of Medical Sciences, 2002, 2(2), 65-73.