Research Article
Mosquitocidal triterpenes from the stem of Duranta repens

Farjana Nikkon, Kazi Abdus Salam, Tanzima Yeasmin, Ashik Mosaddik, Proma Khondkar and M. Ekramul Haque

Pharmaceutical Biology, 2010, 48(3), 264-268. DOI: 10.3109/13880200903096570

Abstract

Two triterpenes, β - amyrin and 12- oleanene 3β, 21β - diol, were isolated as a mixture from the chloroform soluble fraction of an ethanol extract of Duranta repens Linn (Verbenaceae) stem. The structures of the two compounds were confirmed by analysis of their IR, ¹H - NMR, ¹³C - NMR and LC - MS spectral data. The mixture of β - amyrin and 12 - oleanene 3β, 21β - diol (compound 1) was highly effective against the larvae of the mosquito, Culex quinquefasciatus Say (Diptera: Culicidae), as a mosquitocide.

ASCI-ID: 2451-182