Search. Read. Cite.

Easy to search. Easy to read. Easy to cite with credible sources.

Research Article
Natural Products as Therapeutic Agents for Schistosomiasis

Sanaa Ahmed Ali

Research Journal of Medicinal Plants, 2011, 5(1), 1-20.


Schistosomiasis (known as Bilharziasis) is the disease caused by a blood born fluke (trematode) of the genus Schistosoma. The intermediate hosts of all digenetic trematodes are snails and schistosomes are no exception. Adult schistosome worms live in a mammalian host, Schistosomiasis is the second most prevalent tropical disease in Africa after malaria and is of great public health and socio-economic importance in the developing world. This study is to clarify that Natural product extracts with non-toxic medicinal properties should be explored for possible intervention in schistosomiasis as a disease involving impairment of metabolism of infected subjects. These inspire more hope for reducing the intensity of schistosomal infection by reduction in worm burden, ova count, granuloma size and number leading to improvement in histopathological picture of liver, spleen and kidney as a result of reducing inflammatory and fibrotic reactions of schistosoma.

ASCI-ID: 82-91

Cited References Fulltext

Related Articles

Fourier Transform Infrared (FT-IR) Spectroscopy in An-Overview

Research Journal of Medicinal Plants, 2011, 5(2), 127-135.

Cited By

Idiotype/Anti-idiotype Immunoregulatory Network Correlates with an Improved Clinical Outcome of Schistosomiasis mansoni in Humans

Pakistan Journal of Biological Sciences, 2011, 14(6), 375. DOI: 10.3923/pjbs.2011.375.384

Use of Natural Products as Therapeutic Agents for the Treatment of Schistosomiasis

Asian Journal of Animal and Veterinary Advances, 2011, 6(8), 863. DOI: 10.3923/ajava.2011.863.864

Antischistosomal Activity of Two Active Constituents Isolated from the Leaves of Egyptian Medicinal Plants

Infectious Diseases: Research and Treatment, 2015, 8(), IDRT.S24342. DOI: 10.4137/IDRT.S24342

Complementary effect of Capparis spinosa L. and silymarin with/without praziquantel on mice experimentally infected with Schistosoma mansoni

Helminthologia, 2018, 55(1), . DOI: 10.1515/helm-2017-0055

Universal Stress Proteins as New Targets for Environmental and Therapeutic Interventions of Schistosomiasis

International Journal of Environmental Research and Public Health, 2016, 13(12), 972. DOI: 10.3390/ijerph13100972

PZQ Therapy: How Close are we in the Development of Effective Alternative Anti-schistosomal Drugs?

Infectious Disorders - Drug Targets, 2019, 19(4), 337. DOI: 10.2174/1871526519666181231153139

Seabuckthorn (Hippophae rhamnoides L.), a novel seed protein concentrate: isolation and modification by high power ultrasound and characterization for its functional and structural properties

Journal of Food Measurement and Characterization, 2021, (), . DOI: 10.1007/s11694-021-01020-7

Essential oils from three Algerian medicinal plants (Artemisia campestris, Pulicaria arabica, and Saccocalyx satureioides) as new botanical insecticides?

Environmental Science and Pollution Research, 2020, 27(21), 26594. DOI: 10.1007/s11356-020-09064-w

Toxicité aiguë et subaiguë de Garcinia huillensis Baker, plante utilisée contre la schistosomiase urogénitale dans le Haut-Katanga, RD Congo

Annales Pharmaceutiques Françaises, 2020, (), . DOI: 10.1016/j.pharma.2020.11.006