Research Article
Protein adsorption on low temperature alpha alumina films for surgical instruments

A.N. Cloud, S. Kumar, M. Kavdia, H.H. Abu-Safe and M.H. Gordon

Thin Solid Films, 2009, 517(20), 5927-5930. DOI: 10.1016/j.tsf.2008.08.002

Abstract

Bulk alumina has been shown to exhibit reduced protein adsorption, a property that can be exploited for developing alumina-coated surgical instruments and devices. Alpha alumina thin films were deposited on surgical stainless steel substrates to investigate the adsorption of a model protein (BSA, bovine serum albumin). The films were deposited at 480 °C by AC inverted cylindrical magnetron sputtering. Films were obtained at 6 kW and 50% oxygen partial pressure by volume. The presence of alpha-phase alumina has been shown by transmission electron microscopy. Results indicate that there was a 50% reduction in protein adsorption for samples with the alumina coating compared to those with no coating.

ASCI-ID: 479-70