Glu³³² in the Nicastrin Ectodomain Is Essential for γ-Secretase Complex Maturation but Not for Its Activity

Lucia Chavez-Gutierrez, Alexandra Tolia, Elke Maes, Tong Li, Philip C. Wong and Bart de Strooper

The Journal of Biological Chemistry 283 ( 29 ): 20096 - 20105 , 2008