JingSheng Lai, ZhiHui Zhang, LeHua Xie, Xin Liang, XianZhu Liang, HongJian Zhou and QiuNing Pan
International Journal of Pharmacology, 2024, 20(5), 742-747.
Background and Objective: General anesthesia (GN) may cause thoracic surgery patients to lose consciousness and block the Central Nervous System (CNS). The present investigation was carried out to assess the combined effects of the local impact of epidural anaesthesia (EA) with GN in thoracic surgery. Materials and Methods: The investigation included 100 chest surgery participants. The 50 patients were randomly assigned untreated or investigational based on admission time. The investigating group got epidural and GN, whereas the untreated group received general. Both groups’ routine indicators, anaesthesia conditions and surgical side effects were assessed. Results: Both groups had similar preoperative oxygen saturation, systolic and diastolic blood pressure, mean arterial pressure and heart rate (p>0.05). The experimental group showed significant reductions in intraoperative and postoperative blood oxygen saturation, systolic and diastolic blood pressure, mean arterial pressure and heart rate compared to the untreated group (p<0.05). A 32.6±3.4 mL inhaled anaesthetic dose, 9.46±3.61 min intraoperative eye-opening time and 18.13±6.29 min speech function recovery time were seen in the untreated group. Significantly higher than the investigational group (14.2±2.5 mL, 6.1 3±2.78 min) and 9.26±4.07 min, p<0.05. The experimental group had significantly less postoperative side effects than the untreated group (p<0.05). Conclusion: Epidural and GN increase thoracic surgery safety and effectiveness.
ASCI-ID: 23-2027
International Journal of Pharmacology, 2018, 14(6), 826-834.
Effects of Regional and General Anesthesia on Survival in Head and Neck CancerInternational Journal of Pharmacology, 2018, 14(4), 528-533.
Effects of Oral Clonidine in Preventing Postoperative Shivering After General AnesthesiaInternational Journal of Pharmacology, 2007, 3(5), 441-443.