Alanine Scanning Mutagenesis of the Prototypic Cyclotide Reveals a Cluster of Residues Essential for Bioactivity

Shane M. Simonsen, Lillian Sando, K. Johan Rosengren, Conan K. Wang, Michelle L. Colgrave, Norelle L. Daly and David J. Craik

The Journal of Biological Chemistry 283 ( 15 ): 9805 - 9813 , 2008