Three-dimensional Reconstruction of Human Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Revealed an Ellipsoidal Structure with Orifices beneath the Putative Transmembrane Domain

Kazuhiro Mio, Toshihiko Ogura, Muneyo Mio, Hiroyasu Shimizu, Tzyh-Chang Hwang, Chikara Sato and Yoshiro Sohma

The Journal of Biological Chemistry 283 ( 44 ): 30300 - 30310 , 2008