Articles by Isabel Najera (4)

The Hepatitis C Virus Replicon Presents a Higher Barrier to Resistance to Nucleoside Analogs than to Nonnucleoside Polymerase or Protease Inhibitors

Matthew F. McCown, Sonal Rajyaguru, Sophie Le Pogam, Samir Ali, Wen-Rong Jiang, Hyunsoon Kang, Julian Symons, Nick Cammack and Isabel Najera

Antimicrobial Agents and Chemotherapy 52 ( 5 ): 1604 - 1612 , 2008

Selected Replicon Variants with Low-Level In Vitro Resistance to the Hepatitis C Virus NS5B Polymerase Inhibitor PSI-6130 Lack Cross-Resistance with R1479

Samir Ali, Vincent Leveque, Sophie Le Pogam, Han Ma, Friederike Philipp, Nicole Inocencio, Mark Smith, Andre Alker, Hyunsoon Kang, Isabel Najera, Klaus Klumpp, Julian Symons, Nick Cammack and Wen-Rong Jiang

Antimicrobial Agents and Chemotherapy 52 ( 12 ): 4356 - 4369 , 2008

2`-Deoxy-4`-azido Nucleoside Analogs Are Highly Potent Inhibitors of Hepatitis C Virus Replication Despite the Lack of 2`-α-Hydroxyl Groups

Klaus Klumpp, Genadiy Kalayanov, Han Ma, Sophie Le Pogam, Vincent Leveque, Wen-Rong Jiang, Nicole Inocencio, Anniek De Witte, Sonal Rajyaguru, Ezra Tai, Sushmita Chanda, Michael R. Irwin, Christian Sund, Anna Winqist, Tatiana Maltseva, Staffan Eriksson, Elena Usova, Mark Smith, Andre Alker, Isabel Najera, Nick Cammack, Joseph A. Martin, Nils Gunnar Johansson and David B. Smith

The Journal of Biological Chemistry 283 ( 4 ): 2167 - 2175 , 2008

Essential Role of the N-terminal Domain in the Regulation of RIG-I ATPase Activity

Peter Gee, Pong Kian Chua, Jirair Gevorkyan, Klaus Klumpp, Isabel Najera, David C. Swinney and Jerome Deval

The Journal of Biological Chemistry 283 ( 14 ): 9488 - 9496 , 2008

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