The Hepatitis C Virus Replicon Presents a Higher Barrier to Resistance to Nucleoside Analogs than to Nonnucleoside Polymerase or Protease Inhibitors

Matthew F. McCown, Sonal Rajyaguru, Sophie Le Pogam, Samir Ali, Wen-Rong Jiang, Hyunsoon Kang, Julian Symons, Nick Cammack and Isabel Najera

Antimicrobial Agents and Chemotherapy 52 ( 5 ): 1604 - 1612 , 2008